Account 4-((12-((4-(4-Acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)amino)dodecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- Catalog No. :
- ACUZES724
- CAS No. :
- 2984236-79-3
- Molecular Formula :
- C50H54ClFN8O6
- Molecular Weight :
- 917.48
IUPAC Name:4-((12-((4-(4-acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)amino)dodecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pack SizePurityList PriceYour PriceGlobal StockUS StockQuantity
1mg98%$773.00Login to see priceInquiryInquiry
Products of AiFChem are all designed for scientific research only. Under no circumstances do we provide products or services for animal or personal utilization.
0 Reviews:View Reviews
Product Information
| Product Name | 4-((12-((4-(4-Acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)amino)dodecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione |
|---|---|
| IUPAC Name | 4-((12-((4-(4-acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)amino)dodecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione |
| Molecular Formula | C50H54ClFN8O6 |
| Molecular Weight | 917.48 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCCCCCCNC4=NC(N5CCN(C(C=C)=O)CC5)=C6C=C(Cl)C(C7=C8C=CC=CC8=CC(O)=C7)=C(F)C6=N4)=O |
| InChI Key | FMYAMLPDKZOVMB-UHFFFAOYSA-N |
| Synonym | PROTAC KRAS G12C degrader-1;1H-Isoindole-1,3(2H)-dione, 4-[[12-[[6-chloro-8-fluoro-7-(3-hydroxy-1-naphthalenyl)-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-2-quinazolinyl]amino]dodecyl]amino]-2-(2,6-dioxo-3-piperidinyl)- |
| CAS No. | 2984236-79-3 |
Synthetic Route by SureRoute
2. ACUZES724 Molecular Building Block Synthetic Route
PROTAC KRAS G12C degrader-2
3-(5-(4-((4-((1-(2-((4-(3,8-Diazabicyclo[3.2.1]octan-3-yl)-7-(8-ethynyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoropyrido[4,3-d]pyrimidin-2-yl)oxy)ethyl)piperidin-4-yl)methyl)piperidin-1-yl)methyl)piperidin-1-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
(S)-3-(5-(2-((1-((1-(((7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-4-((R)-3-hydroxy-3-methylpiperidin-1-yl)pyrido[4,3-d]pyrimidin-2-yl)oxy)methyl)cyclopropyl)methyl)-4-methylpiperidin-4-yl)methyl)-2,7-diazaspiro[3.5]nonan-7-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione