Aryl-Heteroalicyclic Hybrid Scaffolds (2130)

Unlock New Frontiers in Drug Discovery with AiFChem's Chiral sp3-Enriched Building Blocks.Bridging the gap between flat aromatics and 3D chemical space, our stereodefined scaffolds seamlessly integrate robust binding motifs with optimized physicochemical properties. Engineered for superior solubility and enhanced selectivity, these rigid 3D cores significantly streamline hit-to-lead evolution. Leverage our advanced scaffolds to accelerate rapid library synthesis, unlocking unparalleled possibilities for previously challenging drug targets.

tert-butyl 3-benzyl-4-oxopiperidine-1-carboxylate structure diagram

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Aryl-Heteroalicyclic Hybrid Scaffolds (2130)

tert-butyl 3-benzyl-4-oxopiperidine-1-carboxylate

3-(4-fluorophenoxy)pyrrolidine hydrochloride

6-bromo-2,3-dihydro-1H-inden-5-ol

tert-butyl 6-bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-1-carboxylate

tert-butyl 3-iodo-2-methyl-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate

tert-butyl 4-(6-bromopyridin-2-yl)-1,4-diazepane-1-carboxylate

2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile

tert-butyl 5-oxo-5,7-dihydrospiro[cyclopenta[b]pyridine-6,4'-piperidine]-1'-carboxylate

(4-bromophenyl)(piperidin-4-yl)methanone hydrochloride

spiro[chromane-2,4'-piperidin]-6-ol

tert-butyl 4-chloro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate

6-bromo-4-nitro-2,3-dihydro-1H-inden-5-ol

tert-butyl (1-(4-bromophenyl)cyclopropyl)carbamate

6-bromo-4-fluoro-2,3-dihydro-1H-inden-1-ol

tert-butyl 3-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate

(5-bromo-3-methylpyridin-2-yl)(piperidin-1-yl)methanone

2-Amino-N-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide

(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol

7-benzyl-3-bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine

7-benzyl-4-chloro-2-(methylthio)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

6'-bromospiro[cyclopropane-1,3'-indoline]

3-(3-bromophenyl)oxetan-3-ol

4-(3-fluoro-4-nitrophenyl)morpholine

tert-butyl 6-bromo-3,4-dihydro-1,5-naphthyridine-1(2H)-carboxylate

4-(piperidin-4-yl)benzonitrile

tert-butyl 4-aminospiro[chromane-2,4'-piperidine]-1'-carboxylate

5-bromo-2-(pyrrolidin-1-yl)pyridin-3-amine

2,2,4-trimethyl-1,2-dihydroquinolin-6-ol

methyl 3-(piperidin-4-yl)benzoate hydrochloride

1-(3,5-difluorophenyl)cyclopentan-1-amine