Drug Delivery Systems (DDS) (159)

A drug delivery system is a technical framework designed to regulate the spatial, temporal, and dosage-related distribution of drugs within the body. Its goal is to enhance patient health by optimizing the delivery of therapeutic agents to their target sites while minimizing off-target accumulation. Unlike traditional delivery methods such as oral tablets, capsules, intravenous injections, inhalation preparations, and transdermal patches, modern drug delivery systems leverage advanced technologies with significant technical complexity. These include approaches based on liposomes, nanoparticles, microspheres, exosomes, engineered AAV vectors, and 3D-printed drug formulations. By adjusting drug delivery and release locations, altering drug metabolism within the body, enhancing sustained and controlled-release properties, and enabling penetration of physiological barriers like the blood-brain barrier, these innovative systems improve drug efficacy while reducing toxic side effects.