Linkers and Crosslinkers (142)

Cross-linkers are molecules possessing two or more reactive ends capable of chemically bonding to specific functional groups, such as primary amines or sulfhydryls, on proteins or other molecules. When applied to proteins and biomolecules, this process is commonly referred to as bioconjugation. It plays a critical role in various proteomics techniques, including the development of detectable probes for western blotting and ELISA, as well as approaches for investigating protein structure and interactions.