Nucleoside Phosphoramidites (22)

Phosphoramidite monomers find extensive application in both the chemical and pharmaceutical industries. In the chemical sector, they are primarily utilized in the production of polymer materials like polyamides and polyimides. In the pharmaceutical domain, particularly in molecular biology and genetics, phosphoramidite monomers hold significant importance. For instance, they serve as crucial raw materials in the synthesis of DNA and RNA, where they react with amine groups to form phosphoramide bonds, enabling the attachment of deoxyribose or ribose to bases and facilitating the construction of DNA and RNA molecules. Additionally, phosphoramidite monomers are employed in gene therapy, such as in the synthesis of gene delivery vectors, including plasmids and viral vectors.