Monofunctional PEG and Oligoethylene Glycols (8)

Monofunctional polyethylene glycol (PEG), featuring a single chemically reactive end, is widely utilized in PEGylation, surface modification, and nanoparticle coating. It plays a key role in bioconjugation, surface functionalization, and coating applications. On the other hand, oligopolyethylene glycols (e.g., PEG-2, PEG-4) are primarily employed as solvents and penetration enhancers, aiding in the dissolution of active ingredients, enhancing stability and solubility, and improving the permeability and absorption of oral drugs, thereby boosting bioavailability.