Linkers and Crosslinkers (144)

Cross-linkers are molecules possessing two or more reactive sites that can chemically bind to specific functional groups, such as primary amines or sulfhydryls, on proteins or other biomolecules. This process, commonly termed bioconjugation when applied to proteins and similar substances, plays a crucial role in various proteomics techniques. These include the development of detectable probes for applications like western blotting and ELISA, as well as methods for investigating protein structure and interactions.