Nucleoside Phosphoramidites (130)

Phosphoramidite monomers are extensively utilized in the chemical and pharmaceutical industries. In the chemical sector, they are primarily employed in the synthesis of polymer materials like polyamides and polyimides. In the pharmaceutical domain, particularly in molecular biology and genetics, phosphoramidite monomers hold significant importance. For instance, they serve as essential raw materials in the synthesis of DNA and RNA, enabling the formation of phosphoramide bonds through reactions with amine groups. This allows for the attachment of deoxyribose or ribose to nucleotide bases, facilitating the construction of DNA and RNA molecules. Additionally, phosphoramidite monomers are also applied in gene therapy, such as the synthesis of gene delivery vectors, including plasmids and viral vectors.