Heterobifunctional PEG and Oligoethylene Glycols (84)

Heterobifunctional polyethylene glycol (PEG) possesses distinct functional groups at either end of its chain, enabling selective conjugation between two different molecules or surfaces. These linkers are extensively utilized in bioconjugation reactions to connect molecules or surfaces for achieving specific chemical and biological purposes. Oligopolyethylene glycol (e.g., PEG-2, PEG-4) is primarily employed as a solvent and penetration enhancer, facilitating the dissolution of active ingredients, improving stability and solubility, enhancing the permeability and absorption of oral drugs, and thereby increasing bioavailability.