Linkers and Crosslinkers (144)

Cross-linkers are molecules containing two or more reactive ends that can chemically bind to specific functional groups, such as primary amines or sulfhydryls, on proteins or other substances. This approach, commonly termed bioconjugation when applied to proteins and biomolecules, plays a crucial role in various proteomics techniques. It is used in developing detectable probes for western blotting and ELISA, as well as in methods for investigating protein structure and interactions.