Nucleoside Phosphoramidites (130)

Phosphoramidite monomers are extensively utilized in both the chemical and pharmaceutical industries. In the chemical sector, they are primarily employed in the synthesis of polymeric materials such as polyamides and polyimides. In the pharmaceutical domain, particularly in molecular biology and genetics, phosphoramidite monomers hold significant importance. For instance, they serve as essential raw materials in the synthesis of DNA and RNA, where they react with amine groups to form phosphoramide bonds, linking deoxyribose or ribose to nucleobases to construct DNA and RNA molecules. Additionally, phosphoramidite monomers find applications in gene therapy, including the synthesis of gene vectors such as plasmids and viral vectors.