Heterobifunctional PEG and Oligoethylene Glycols (84)

Heterobifunctional polyethylene glycol (PEG) possesses distinct functional groups at each end of its chain, enabling selective conjugation between two different molecules or surfaces. These linkers are commonly employed in bioconjugation reactions to connect various molecules or surfaces, facilitating specific chemical and biological functions. Meanwhile, oligopolyethylene glycol (e.g., PEG-2, PEG-4) is primarily utilized as a solvent and penetration enhancer, aiding in the dissolution of active ingredients, improving stability and solubility, enhancing oral drug permeability and absorption, and ultimately increasing bioavailability.