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Proteolysis Targeting Chimera Research Reagents (904)

PROTACs are small molecule ligands designed to bind a target protein and recruit an E3 ubiquitin ligase, facilitating the protein's ubiquitination and subsequent degradation via the proteasome system. These tools are employed in studying protein function, identifying new drug targets, and developing innovative therapeutic approaches for conditions like cancer and neurodegenerative diseases.

butane-1,4-disulfonic acid structure diagram

butane-1,4-disulfonic acid

ACYEQC971

27665-39-0

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3-(5-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione structure diagram

3-(5-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

ACCPEF288

1198787-23-3

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di-tert-butyl 4,7,13,16-tetraoxa-10-azanonadecanedioate structure diagram

di-tert-butyl 4,7,13,16-tetraoxa-10-azanonadecanedioate

ACZKIY780

1964503-36-3

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7-((tert-butoxycarbonyl)amino)heptanoic acid structure diagram

7-((tert-butoxycarbonyl)amino)heptanoic acid

ACZJSA347

60142-89-4

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3-(4-iodo-1-oxoisoindolin-2-yl)piperidine-2,6-dione structure diagram

3-(4-iodo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

ACWTHN172

2207541-30-6

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dec-9-ynoic acid structure diagram

dec-9-ynoic acid

ACWSFB230

1642-49-5

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2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethan-1-ol structure diagram

2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethan-1-ol

ACVQAF407

86770-74-3

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2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione structure diagram

2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione

ACUZMB740

64567-60-8

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4-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride structure diagram

4-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

ACUFZG036

444287-40-5

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3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)propanamide structure diagram

3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)propanamide

ACTMPR536

2328070-52-4

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2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione structure diagram

2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

ACTKPJ105

50-35-1

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14-amino-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide hydrochloride structure diagram

14-amino-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide hydrochloride

ACSQPC196

2331259-45-9

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1-(8-bromoimidazo[1,2-a]pyridin-3-yl)dihydropyrimidine-2,4(1H,3H)-dione structure diagram

1-(8-bromoimidazo[1,2-a]pyridin-3-yl)dihydropyrimidine-2,4(1H,3H)-dione

ACSQLA728

2713620-89-2

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3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methoxybenzoic acid structure diagram

3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methoxybenzoic acid

ACPCMW574

2377643-33-7

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4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione structure diagram

4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

ACOLIV156

1818885-63-0

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2,2-dimethyl-4-oxo-3,7,10,13,16,19,22-heptaoxapentacosan-25-oic acid structure diagram

2,2-dimethyl-4-oxo-3,7,10,13,16,19,22-heptaoxapentacosan-25-oic acid

ACNRZE608

2093153-84-3

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3-(3-aminophenyl)piperidine-2,6-dione structure diagram

3-(3-aminophenyl)piperidine-2,6-dione

ACNIOS168

1512414-62-8

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4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione structure diagram

4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

ACMFGQ641

19171-19-8

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tetradec-13-ynoic acid structure diagram

tetradec-13-ynoic acid

ACKRDT180

82909-47-5

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1-(6-bromo-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione structure diagram

1-(6-bromo-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione

ACKIOW927

2446913-88-6

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tert-butyl bis(2-(2-hydroxyethoxy)ethyl)carbamate structure diagram

tert-butyl bis(2-(2-hydroxyethoxy)ethyl)carbamate

ACKBMD164

275385-03-0

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tert-butyl bis(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)carbamate structure diagram

tert-butyl bis(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)carbamate

ACJDIR364

2093154-01-7

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2-(2,6-dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione structure diagram

2-(2,6-dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione

ACIXJK315

2226303-74-6

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tert-butyl 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoate structure diagram

tert-butyl 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoate

ACIBQU371

2225148-52-5

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3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methylbenzoic acid structure diagram

3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-methylbenzoic acid

ACDJMA891

2377643-37-1

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(S)-2-((S)-1-((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoic acid structure diagram

(S)-2-((S)-1-((S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)propanamido)-2-cyclohexylacetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoic acid

ACCSOP051

1073560-68-5

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2-(2,6-dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione structure diagram

2-(2,6-dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione

ACCNLW938

40313-92-6

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2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carboxylic acid structure diagram

2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carboxylic acid

ACALCT785

1547163-38-1

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tert-butyl 2-(2-(2-aminoethoxy)ethoxy)acetate structure diagram

tert-butyl 2-(2-(2-aminoethoxy)ethoxy)acetate

ACWMKU819

1122484-77-8

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tert-butyl 3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)propanoate structure diagram

tert-butyl 3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)propanoate

ACVGAS401

252881-74-6

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Total: 601

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