EGFR (272)

The epidermal growth factor receptor (EGFR) is a transmembrane protein tyrosine kinase that serves as a receptor for the EGF family, activating the EGFR signaling pathway in human epithelial cells. This pathway plays a critical role in regulating processes such as cell proliferation, invasion, metastasis, apoptosis, and angiogenesis. EGFR overexpression and mutations are strongly associated with the progression of non-small cell lung cancer (NSCLC) and represent a significant and valuable therapeutic target for this disease.

1-(methylsulfonyl)indolin-7-amine structure diagram

Total: 45

Recently Added

EGFR (272)

1-(methylsulfonyl)indolin-7-amine

methyl 3-fluoro-5-iodo-2-methylbenzoate

3-(4-bromo-2,6-difluorophenyl)piperidine-2,6-dione

8-bromo-3-chloro-5-isopropylisoquinoline

3-fluoro-1-methyl-1H-pyrazol-4-amine

4-bromo-3-(difluoromethoxy)-1-methyl-1H-pyrazole

4-chloro-6,7-difluoroquinazoline

4-bromo-1-methyl-1,2-dihydro-3H-pyrazol-3-one

4-chloro-3-fluoropicolinaldehyde

(S)-tetrahydrofuran-3-ol

(E)-4-(dimethylamino)but-2-enoic acid hydrochloride

(3-((dimethylamino)methyl)oxetan-3-yl)methanol

4-fluoro-2-methoxy-5-nitroaniline

4-amino-2,2-dimethylcyclohexan-1-ol hydrochloride

(4-amino-2-iodophenyl)methanol

(2S,3S)-2-methyl-3-((methylsulfonyl)methyl)azetidine hydrochloride

(E)-4-(piperidin-1-yl)but-2-enoic acid hydrochloride

3-(tert-butoxycarbonyl)-6,6-difluoro-3-azabicyclo[3.1.0]hexane-1-carboxylic acid

(2-amino-4-fluorophenyl)dimethylphosphine oxide

(2R,3S)-2-methyl-3-((methylsulfonyl)methyl)azetidine hydrochloride

3-chloro-5-methoxyisoquinoline

4-chloro-7-fluoro-6-nitroquinazoline

6-hydroxy-7-methoxyquinazolin-4(1H)-one

2,6-bis(benzyloxy)-3-(4-bromo-2,6-difluorophenyl)pyridine

(2-amino-6-fluorophenyl)dimethylphosphine oxide

(2S,3R)-2-methyl-3-((methylsulfonyl)methyl)azetidine hydrochloride

4-(3-chloropropyl)morpholine

2-(1-methoxyethyl)aniline

4-chloro-6-methoxy-1,7-naphthyridine

(2R,3R)-2-methyl-3-((methylsulfonyl)methyl)azetidine hydrochloride