KIF18A (49)

KIF18A is a kinesin motor protein essential for mitosis, particularly in regulating chromosome alignment during cell division. It facilitates the transport of microtubules to the mitotic spindle, ensuring proper chromosome segregation. Abnormal expression or regulation of KIF18A has been linked to various cancers, as it can lead to chromosomal instability and promote tumor progression. Given its critical role in cell division, KIF18A has become a promising therapeutic target for cancer, with inhibitors being studied for their potential to hinder tumor cell proliferation.