IL-17A (170)

IL-17A is a pro-inflammatory cytokine produced by T helper 17 (Th17) cells, essential for immune responses, particularly in pathogen defense and the development of autoimmune diseases. It facilitates neutrophil recruitment and stimulates the release of additional cytokines, thereby intensifying inflammation. Aberrant IL-17A signaling is linked to various chronic inflammatory conditions, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Therapeutic strategies targeting IL-17A or its receptor have demonstrated promise in mitigating inflammation and preventing tissue damage, positioning it as a valuable target for immune-modulatory treatments.