(R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide

Catalog No. :: ACJSRP487
CAS No. :: 1855860-24-0
Molecular Formula :: C41H42FN5O7
Molecular Weight :: 735.81

IUPAC Name:DS-1205b

(R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide structure diagram

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Product Information

Product Name	(R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide
IUPAC Name	DS-1205b
Molecular Formula	C41H42FN5O7
Molecular Weight	735.81
SMILES	O=C(C1=CN(CC2CCOCC2)C=C(C3=NC=C(C)C=C3)C1=O)NC4=CC=C(C5=CC(C6=CC=C(OC[C@@H]7OCCOC7)C(OC)=C6)=CN=C5N)C(F)=C4
InChI Key	ZOEILZXFYPPMTR-SSEXGKCCSA-N
Synonym	[2,3'-Bipyridine]-5'-carboxamide, N-[4-[2-amino-5-[4-[(2R)-1,4-dioxan-2-ylmethoxy]-3-methoxyphenyl]-3-pyridinyl]-3-fluorophenyl]-1',4'-dihydro-5-methyl-4'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)methyl]-;DS-1206b;DS-1206;DS-1205;DS-1205b free base;TRKA,c-Met/HGFR,migration,Axl,Tyro3,Trk Receptor,MET,DS 1205,Mer,Tropomyosin related kinase receptor,tumor,DS1205,kinase,inhibit,Inhibitor,DS-1205b,TAM Receptor,NIH3T3;2,3'-Bipyridine]-5'-carboxamide, N-[4-[2-amino-5-[4-[(2R)-1,4-dioxan-2-ylmethoxy]-3-methoxyphenyl]-3-pyridinyl]-3-fluorophenyl]-1',4'-dihydro-5-methyl-4'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)methyl]-;N-{4-[2-amino-5-(4-{[(2R)-1,4-dioxan-2-yl]methoxy}-3-methoxyphenyl)pyridin-3-yl]-3-fluorophenyl}-5-methyl-1'-[(oxan-4-yl)methyl]-4'-oxo-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide
CAS No.	1855860-24-0
PubChem CID	129110632

Synthetic Route by SureRoute

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ACJSRP4871855860-24-0

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ACJSRP4871855860-24-0

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(R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide

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Synthetic Route by SureRoute

1. ACJSRP487 Molecular Building Block Synthetic Route

2. ACJSRP487 Molecular Building Block Synthetic Route

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(R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide

Product Information

Synthetic Route by SureRoute

Axl-IN-8

AXL-IN-14

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