Account TREM2 agonist-1
- Catalog No. :
- ACTXBT049
- CAS No. :
- 2738486-70-7
- Molecular Formula :
- C23H21ClFN5O
- Molecular Weight :
- 437.91
IUPAC Name:5-(4-chloro-2-fluorophenyl)-2-methyl-7-((2S,4S)-2-(1-methyl-1H-pyrazol-4-yl)tetrahydro-2H-pyran-4-yl)pyrido[3,4-b]pyrazine
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Product Information
| Product Name | TREM2 agonist-1 |
|---|---|
| IUPAC Name | 5-(4-chloro-2-fluorophenyl)-2-methyl-7-((2S,4S)-2-(1-methyl-1H-pyrazol-4-yl)tetrahydro-2H-pyran-4-yl)pyrido[3,4-b]pyrazine |
| Molecular Formula | C23H21ClFN5O |
| Molecular Weight | 437.91 |
| SMILES | CN1N=CC([C@@H]2C[C@@H](C3=NC(C4=CC=C(Cl)C=C4F)=C(N=CC(C)=N5)C5=C3)CCO2)=C1 |
| InChI Key | ZXFBVRXQVXFOIP-QKKBWIMNSA-N |
| Synonym | Pyrido[3,4-b]pyrazine, 5-(4-chloro-2-fluorophenyl)-2-methyl-7-[(2S,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]-;TREM2 agonist-1 |
| CAS No. | 2738486-70-7 |
Synthetic Route by SureRoute
2. ACTXBT049 Molecular Building Block Synthetic Route
5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-((2R,4S)-2-(1-methyl-1H-pyrazol-4-yl)tetrahydro-2H-pyran-4-yl)pyrido[3,4-b]pyrazine
Rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine
![(R,Sp)-[2-(4'-i-Propyloxazolin-2'-yl)ferrocenyl]diphenylphosphine structure diagram](https://xchemchain-prod-1253699568.cos.ap-guangzhou.myqcloud.com/production/attachments/2026/07/22/6e8q/541540-70-9.png?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIDT0SoARehYSEnT2RxQiomY7TcckkZDlIx%2F20260731%2Fap-guangzhou%2Fs3%2Faws4_request&X-Amz-Date=20260731T105254Z&X-Amz-Expires=86400&X-Amz-SignedHeaders=host&response-content-disposition=attachment%3B%20filename%3D%22541540-70-9.png%22&x-id=GetObject&X-Amz-Signature=c84427b58726c5e591d89428fab31085f2196114024360fa3239027d720bb669)
(R,Sp)-[2-(4'-i-Propyloxazolin-2'-yl)ferrocenyl]diphenylphosphine
![(2Rp)-1-[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl]-2-(diphenylphosphino)ferrocene structure diagram](https://xchemchain-prod-1253699568.cos.ap-guangzhou.myqcloud.com/production/attachments/2026/07/22/qu6t/291536-01-1.png?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIDT0SoARehYSEnT2RxQiomY7TcckkZDlIx%2F20260731%2Fap-guangzhou%2Fs3%2Faws4_request&X-Amz-Date=20260731T113932Z&X-Amz-Expires=86400&X-Amz-SignedHeaders=host&response-content-disposition=attachment%3B%20filename%3D%22291536-01-1.png%22&x-id=GetObject&X-Amz-Signature=69c9e5f406e788652d93a447156dd44c7481e4f53f35a65aefefe73a15153158)