Account PF-06663195
- Catalog No. :
- ACYMAW293
- CAS No. :
- 1621585-22-5
- Molecular Formula :
- C18H18F3N3O2S
- Molecular Weight :
- 397.42
IUPAC Name:(4S,4aR,6R,8aS)-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-6-(3-methylisoxazol-5-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine
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Product Information
| Product Name | PF-06663195 |
|---|---|
| IUPAC Name | (4S,4aR,6R,8aS)-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-6-(3-methylisoxazol-5-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine |
| Molecular Formula | C18H18F3N3O2S |
| Molecular Weight | 397.42 |
| SMILES | C(F)[C@@H]1[C@]2([C@](CO[C@H](C2)C3=CC(C)=NO3)(N=C(N)S1)C4=C(F)C=C(F)C=C4)[H] |
| InChI Key | JIAYOIBUKDISBO-IYPIGGPWSA-N |
| Synonym | Pyrano[3,4-d][1,3]thiazin-2-amine, 8a-(2,4-difluorophenyl)-4-(fluoromethyl)-4,4a,5,6,8,8a-hexahydro-6-(3-methyl-5-isoxazolyl)-, (4S,4aR,6R,8aS)-;PF-06663195 >=98% (HPLC);PF-06663195 |
| CAS No. | 1621585-22-5 |
Synthetic Route by SureRoute
2. ACYMAW293 Molecular Building Block Synthetic Route
N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-(difluoromethyl)pyrazine-2-carboxamide
(1R)-1-[Bis(2-methoxyphenyl)phosphino]-2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]ferrocene
![(R)-N,N-Dimethyl-1-[(Rp)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine structure diagram](https://xchemchain-prod-1253699568.cos.ap-guangzhou.myqcloud.com/production/attachments/2026/07/22/roob/74311-56-1.png?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIDT0SoARehYSEnT2RxQiomY7TcckkZDlIx%2F20260808%2Fap-guangzhou%2Fs3%2Faws4_request&X-Amz-Date=20260808T041748Z&X-Amz-Expires=86400&X-Amz-SignedHeaders=host&response-content-disposition=attachment%3B%20filename%3D%2274311-56-1.png%22&x-id=GetObject&X-Amz-Signature=9a2fc8283fe7834ec698e93257910e52922e1053d2985866f5df5899b164e59a)
(R)-N,N-Dimethyl-1-[(Rp)-1′,2-bis(diphenylphosphino)ferrocenyl]ethylamine
![1-Dicyclohexylphosphino-1'-{(S)-{(SP)-2-[(R)-1-(dimethylamino)ethyl]Ferrocenyl}phenylphosphino}Ferrocene structure diagram](https://xchemchain-prod-1253699568.cos.ap-guangzhou.myqcloud.com/production/attachments/2026/07/22/xz17/952586-19-5.png?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIDT0SoARehYSEnT2RxQiomY7TcckkZDlIx%2F20260808%2Fap-guangzhou%2Fs3%2Faws4_request&X-Amz-Date=20260808T041748Z&X-Amz-Expires=86400&X-Amz-SignedHeaders=host&response-content-disposition=attachment%3B%20filename%3D%22952586-19-5.png%22&x-id=GetObject&X-Amz-Signature=00d5c2aa3b7b26e6371af05f39dd28230b90b584e9e9de68998dc44cfcec80d3)