Account Afeletecan HCl
- Catalog No. :
- ACYQCJ086
- CAS No. :
- 215604-74-3
- Molecular Formula :
- C45H50ClN7O11S
- Molecular Weight :
- 932.45
IUPAC Name:(S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate hydrochloride
Pack SizePurityList PriceYour PriceGlobal StockUS StockQuantity
No pack options available.
Products of AiFChem are all designed for scientific research only. Under no circumstances do we provide products or services for animal or personal utilization.
0 Reviews:View Reviews
Product Information
| Product Name | Afeletecan HCl |
|---|---|
| IUPAC Name | (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate hydrochloride |
| Molecular Formula | C45H50ClN7O11S |
| Molecular Weight | 932.45 |
| SMILES | CC(C)[C@@H](C(O[C@](C1=C(CO2)C(N3CC4=CC5=CC=CC=C5N=C4C3=C1)=O)(CC)C2=O)=O)NC([C@H](CC6=CNC=N6)NC(NC7=CC=C(O[C@@H]8[C@@H](O)[C@H](OC)[C@H](O)[C@H](C)O8)C=C7)=S)=O.[H]Cl |
| InChI Key | XQWYWSHYKUJQDC-NZGUGFNHSA-N |
| Synonym | BAY 38-3441 free base;L-Valine, N-[[[4-[(6-deoxy-3-O-methyl-b-L-galactopyranosyl)oxy]phenyl]amino]thioxomethyl]-L-histidyl-, (4S)-4-ethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl e_x000D_ ster;Afeletecan HCl;BAY 56-3722 hydrochloride |
| CAS No. | 215604-74-3 |
Synthetic Route by SureRoute
2. ACYQCJ086 Molecular Building Block Synthetic Route
Afeletecan free base
MAC glucuronide α-hydroxy lactone-linked SN-38
S-(1-((4-(((1-((S)-37-amino-34-((4-((((((S)-4,11-diethyl-9-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl)oxy)carbonyl)oxy)methyl)phenyl)carbamoyl)-28,32-dioxo-3,6,9,12,15,18,21,24,30-nonaoxa-27,33-diazaheptatriacontyl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)cyclohexyl)methyl)-2,5-dioxopyrrolidin-3-yl)-L-cysteine