Account rel-Lifirafenib
- Catalog No. :
- ACYXQD216
- CAS No. :
- 1446090-77-2
- Molecular Formula :
- C25H17F3N4O3
- Molecular Weight :
- 478.43
IUPAC Name:5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
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Product Information
| Product Name | rel-Lifirafenib |
|---|---|
| IUPAC Name | 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one |
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.43 |
| SMILES | O=C1NC2=C(C(OC3=CC=C(O[C@@]4([H])[C@]5([H])[C@@H]4C6=NC7=CC=C(C(F)(F)F)C=C7N6)C5=C3)=CC=N2)CC1 |
| InChI Key | NGFFVZQXSRKHBM-FKBYEOEOSA-N |
| Synonym | 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one;BGB-283;BGB-283,GDC-0810;BGB-TG-P1;bgb283(Lifirafenib);BGB-283;BGB 283;CS-2387;LIFIRAFENIB (BGB-283) |
| CAS No. | 1446090-77-2 |
Safety Data
- Pictogram
- Signal Word
- Warning
- Hazard Statement(s)
- H302-H315-H319
- Precautionary Statement(s)
- P264-P270-P280-P301+P312+P330-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364-P501
Synthetic Route by SureRoute
2. ACYXQD216 Molecular Building Block Synthetic Route
5-(((1R,1aS,6bR)-1-(6-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
5-((3-(5-(2-Chlorophenyl)-1H-imidazol-2-yl)chroman-6-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
(1S,1AS,6bR)-5-((7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-1-carboxylic acid