Account (R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide
- Catalog No. :
- ACZTEG332
- CAS No. :
- 1223404-68-9
- Molecular Formula :
- C22H23F2N5O2
- Molecular Weight :
- 427.45
IUPAC Name:(R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide
![(R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide structure diagram](/images/productimg/no-pic.svg)
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Product Information
| Product Name | (R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide |
|---|---|
| IUPAC Name | (R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide |
| Molecular Formula | C22H23F2N5O2 |
| Molecular Weight | 427.45 |
| SMILES | O=C(NC1=C2N=C(N3CCC[C@@H]3C3=CC(F)=CC=C3F)C=CN2C=C1)N1CC[C@@H](O)C1 |
| InChI Key | XRRANUQMDIVOON-DNVCBOLYSA-N |
| Synonym | (R)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide;Larotrectinib impurity;Larotrectinib Impurity 8;(R)-N-(2-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrrolo[1,2-a]pyrimidin-8-yl)-3-hydroxypyrrolidine-1-carboxamide;Larotrectinib Impurity 2;Larotrectinib Impurity 7;(R)-Larotrectinib;1-Pyrrolidinecarboxamide, N-[5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-, (3R)- |
| CAS No. | 1223404-68-9 |
Synthetic Route by SureRoute
2. ACZTEG332 Molecular Building Block Synthetic Route
(S)-N-(5-((R)-2-(2,5-Difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
(S)-N-(5-((R)-2-(2,5-Difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrochloride
(R)-N-(5-((S)-2-(2,5-Difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide